Consider the following guidelines for optimization of the device performance:
Do not turn off the lamp or lamps during short measurement breaks. Igniting a lamp frequently reduces the lifetime of the lamp. In addition, some time is required for the detector to stabilize after re-ignition of a lamp.
Degas the solvent.
Consider the influences of the parameters on the detection.
Keep the device doors closed during operation to avoid exposure of the flow cell to thermal changes in the environment that may lead to a baseline drift.
Ensure that the operating conditions are suitable. This includes:
Stable environmental conditions, such as a stable temperature
No air drafts
No vibrations or mechanical shocks caused by external sources
No EMC-related sources of strong interference. Operate only certified laboratory equipment in close proximity to the detector.
Stable backpressure and correct waste line setup
Monitor the usage of specific components that are subject to wear and stress and schedule appropriate maintenance intervals (see Predictive Performance).
Observe the general guidelines and recommendations on the use of solvents and additives in the chromatography system. Refer to Use of Solvents and Additives in the Vanquish System Operating Manual.