Consider the following guidelines for optimization of the device performance:

  • Do not turn off the lamp or lamps during short measurement breaks. Igniting a lamp frequently reduces the lifetime of the lamp. In addition, some time is required for the detector to stabilize after re-ignition of a lamp.

  • Degas the solvent.

  • Consider the influences of the parameters on the detection.

  • Keep the device doors closed during operation to avoid exposure of the flow cell to thermal changes in the environment that may lead to a baseline drift.

  • Ensure that the operating conditions are suitable. This includes:

    • Stable environmental conditions, such as a stable temperature

    • No air drafts

    • No vibrations or mechanical shocks caused by external sources

    • No EMC-related sources of strong interference. Operate only certified laboratory equipment in close proximity to the detector.

    • Stable backpressure and correct waste line setup

  • Monitor the usage of specific components that are subject to wear and stress and schedule appropriate maintenance intervals (see Predictive Performance).

  • Observe the general guidelines and recommendations on the use of solvents and additives in the chromatography system. Refer to Use of Solvents and Additives in the Vanquish System Operating Manual.