Solvent Lines and Solvent Line Filters - Dual Pump C - Isocratic Pump C - Dual Pump CN - Quaternary Pump C - Quaternary Pump F - Binary Pump C - Binary Pump F - Dual Pump F - Vanquish Pumps C, Pumps F (VC-Pxx, VF-Pxx) Operating Manual - Maintenance and Service - Solvent Lines and Solvent Line Filters - Dual Pump C - Isocratic Pump C - Dual Pump CN - Quaternary Pump C - Quaternary Pump F - Binary Pump C - Binary Pump F - Dual Pump F

Vanquish Pumps C, Pumps F (VC-Pxx, VF-Pxx) Operating Manual

Product Tree
Chromatography > Liquid Chromatography > Vanquish Series > Vanquish Core HPLC > Dual Pump C
Chromatography > Liquid Chromatography > Vanquish Series > Vanquish Core HPLC > Isocratic Pump C
Chromatography > Liquid Chromatography > Vanquish Series > Vanquish Core HPLC > Dual Pump CN
Chromatography > Liquid Chromatography > Vanquish Series > Vanquish Core HPLC > Quaternary Pump C
Chromatography > Liquid Chromatography > Vanquish Series > Vanquish Flex UHPLC > Quaternary Pump F
Chromatography > Liquid Chromatography > Vanquish Series > Vanquish Core HPLC > Binary Pump C
Chromatography > Liquid Chromatography > Vanquish Series > Vanquish Flex UHPLC > Binary Pump F
Chromatography > Liquid Chromatography > Vanquish Series > Vanquish Flex UHPLC > Dual Pump F
Document Type
Operating Manual
  • Vanquish Pumps C, Pumps F
  • Using this Manual
  • About this Manual
  • Conventions
  • Conventions for Safety Messages
  • Special Notices
  • Typographical Conventions
  • Reference Documentation
  • Safety
  • Safety Symbols and Signal Words
  • Safety Symbols and Signal Words in this Manual
  • Observing this Manual
  • Safety Symbols on the Device
  • Rating Plate
  • Intended Use
  • Safety Precautions
  • General Safety Information
  • Qualification of the Personnel
  • Personal Protective Equipment
  • Electrical Safety Precautions
  • General Residual Hazards
  • In Case of Emergency
  • Solvent and Additive Information
  • General Compatibility
  • Piston Seal Compatibility
  • Allowed pH Ranges
  • Allowed Concentrations
  • Further Information
  • Compliance Information
  • Device Overview
  • Pump Features
  • Operating Principle
  • Interior Components
  • Piston Seal Wash System
  • Purge/Sensor Unit
  • Mixing System
  • Leak Detection
  • Operation
  • Unpacking
  • Unpacking
  • Scope of Delivery
  • Installation
  • Safety Guidelines for Installation
  • Installing the Device
  • Site Requirements
  • Power Considerations
  • Power Cord
  • Condensation
  • Accessing the Interior Components
  • Setting Up the Hardware
  • System Arrangement
  • Connecting the Device
  • Connecting the Power Cord
  • Setting Up the Flow Connections
  • General Information and Guidelines
  • Guiding Capillaries and Tubing Through the System
  • Connecting Fittings, Capillaries, and Tubing
  • General Guidelines
  • Connecting Viper Capillaries
  • Connecting Non-Viper Capillaries
  • Guiding Liquids to Waste
  • Connecting the Solvent Lines
  • Installing Solvent Shut-Off Valves
  • Seal Wash System
  • Choosing the Seal Wash Liquid
  • Setting Up the Seal Wash System
  • Flushing the Seal Wash System
  • Connecting the Pump and Autosampler
  • Turning On the Device
  • Setting Up the Device in the Software
  • Operation
  • Introduction to this Chapter
  • Safety Guidelines for Operation
  • Control Elements
  • Keypad
  • Status Indicators
  • Power On/Off Control
  • Use of Solvents and Additives
  • Preparing the Device for Operation
  • Important Operating Parameters
  • Purging the Pump
  • Automatic Purging
  • Manual Purging
  • Purging with First Time Operation or Empty Solvent Lines
  • Purging for Removing Air Bubbles or Changing to Different Solvent Type
  • Optimizing the Performance of the Device
  • General Guidelines
  • Installing Solvent Shut-Off Valves
  • Shutting Down the Device
  • Short-Term Shutdown (Interruption of Operation)
  • Long-Term Shutdown
  • Restart after Long-Term Shutdown
  • Maintenance and Service
  • Introduction to Maintenance and Service
  • Safety Guidelines for Maintenance and Service
  • General Rules for Maintenance and Service
  • Routine and Preventive Maintenance
  • Internal Maintenance
  • Maintenance Plan
  • Flushing the Pump to Avoid Contamination
  • Flushing the Pump with Persistent Contamination Only
  • Cleaning or Decontaminating the Device
  • Predictive Performance
  • Seal Wash System
  • Testing the Seal Wash System for Leakage
  • Replacing the Seal Wash Lines
  • Replacing the Seal Wash Detector
  • Pump Head
  • Overview of Pump Head Parts
  • Replacing the Pump Head
  • Removing the Pump Head
  • Installing the Pump Head
  • Flushing the Seal Wash System
  • Replacing the Pistons
  • Cleaning the Piston
  • Replacing the Piston Seals or Support Ring
  • Recommendations for New Piston Seals
  • Replacing the Seal Wash Seals
  • Replacing the Pump Head Seals
  • Testing the Piston Seals for Leakage
  • Check Valves
  • Replacing the Inlet Check Valves
  • Replacing the Outlet Check Valves
  • Cleaning the Check Valves
  • Mixing System
  • Testing the Static Mixer for Permeability
  • Replacing the Static Mixer or Capillary Mixer
  • Solvent Lines and Solvent Line Filters
  • Emptying the Solvent Lines
  • Replacing Solvent Lines
  • Solvent Lines From Reservoir To Pump Inlet
  • Solvent Lines From Pump Inlet to Proportioning Valve or Degasser
  • Solvent Line From Proportioning Valve or Degasser To Pump Head
  • Replacing the Solvent Line Filter
  • Replacing the Purge Valve Knob
  • Testing the Pump for Leakage (General Test)
  • Automatic Testing
  • Manual Testing
  • Replacing the Main Power Fuses
  • Updating the Device Firmware
  • Replacing the Doors
  • Transporting or Shipping the Device
  • Preparing the Device for Transport
  • Transporting the Device to a New Location
  • Shipping the Device
  • Replacing the Slide-In Module
  • Removing the Slide-In Module
  • Returning the Slide-In Module
  • Installing the Slide-In Module
  • Setting Up the Slide-In Module
  • Troubleshooting
  • General Information about Troubleshooting
  • Messages
  • Testing the Pump for Leakage
  • Resolving Liquid Leaks
  • Pressure Issues or Shifts in Retention Time
  • Pressure Not Zero with Open Purge Valve
  • Checking the Compression Values
  • Testing the Static Mixer for Permeability
  • Removing Persistent Air Bubbles
  • Pump-Specific Information
  • Introduction to this Chapter
  • Quaternary Pump and Dual Pump
  • Interior Components (Quaternary Pump)
  • Interior Components (Dual Pump)
  • Operating Principle
  • Dwell Volume of the Pump
  • Setting the Solvent Composition
  • Synchronizing the Injection Time with the Pump Strokes
  • Dual Pump Specifics
  • Sharing the Dual Pump
  • Monitoring the Solvent Consumption
  • Monitoring the Liquid Level in the Waste Container
  • Binary Pump
  • Interior Components
  • Operating Principle
  • Dwell Volume of the Pump
  • Setting the Solvent Composition
  • Isocratic Pump
  • Interior Components
  • Operating Principle
  • Modifying the Pump for Specific Applications
  • Gradient Delay Volume, Dwell Volume and Ripple
  • Available Mixing Systems
  • Exchanging the Mixing System
  • Removing the Mixing System
  • Installing a Mixing System with a Volume higher than 100 µL
  • Installing the 100 µL Mixing System
  • Installing the 35 µL Inline Filter Set
  • Normal-Phase Compatible Solvents and Additives
  • Specifications
  • Performance Specifications
  • Quaternary Pump and Dual Pump
  • Binary Pump
  • Isocratic Pump
  • Physical Specifications
  • Accessories, Consumables and Replacement Parts
  • General Information
  • Ship Kit
  • Binary Pump
  • Dual Pump
  • Isocratic Pump
  • Quaternary Pump
  • Optional Accessories
  • Optional Accessories (Miscellaneous)
  • Optional Mixing Systems and Inline Filters
  • Consumables and Replacement Parts
  • Maintenance Kits
  • Maintenance Kits (VC-Pumps)
  • Maintenance Kits (VF-Pumps)
  • Pump Heads and Components
  • Pump Heads and Components (VC-Pumps)
  • Pump Heads and Components (VF-Pumps)
  • Solvents and Wash Systems
  • Mixing Systems
  • Miscellaneous Parts
  • Interface Cables and Power Cords
  • Appendix
  • Compliance Information
  • Declarations of Conformity
  • WEEE Compliance
  • FCC Compliance
  • Manual Release History
  • Digital I/O

Follow the sequence of steps for the maintenance procedure that you want to perform:

  • To empty the solvent lines, see Emptying the Solvent Lines.

  • To replace solvent lines, see Replacing Solvent Lines.

  • To replace the solvent line filter, see Replacing the Solvent Line Filter.

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