General preparations
Run the script: B05 - Shutdown (Long-term) with the following parameter: Module to remove = Column Compartment.
To be able to shift the system base slightly on the workbench for better access to system parts, unlock the system base using the system base locking tools. See Unlocking the System Base.
Move the system stack into an appropriate working position.
Shutdown
Turn off all system modules with their main power switch. Pressing the system power button will not be sufficient to turn off the power to the devices completely.
Disconnect the power cord.
Disconnect all signal cables to other devices.
Flow connections
Remove all flow connections to other system modules.
Cover open switching valve ports with fitting plugs.
NOTICE
Flow connections and capillary connectors are highly sensitive to contamination. Dust and debris can contaminate these connections.
Optional accessories
Remove the column following the instructions in Installing Columns in the Column Compartment in reverse order.
Remove the pre-heater, if installed (see Replacing the Passive Pre-Heater).
Remove the switching valves (see Replacing the Vanquish Switching Valve or Replacing the VICI Switching Valve).
Cleaning
Check the leak tray and drain port. If liquid is present, absorb the liquid with a tissue.