Regularly test the system for leaks for the following liquids:

Liquid

Follow the instructions in…

Solvent

This section

Seal wash liquid

Testing the Seal Wash System for Leakage

Solvent and needle wash liquid from the autosampler valves

Inspecting the Autosampler Valves for Leakage

Condensing water from the autosampler

Testing the Drain Pump Tubing

When

  • Regularly (as part of the maintenance plan):

    • After replacing the solvent reservoirs

    • After changing the workflow

  • A leak sensor reports leakage.

  • Chromatography problems:

    • Peaks are too small

    • Variations in retention time

Parts and additional items required

  • Replacement part as required

  • Cloth or tissue

Preparations

When resolving leakage, observe the safety guidelines and general rules for maintenance and service as presented in Maintenance and Service.

Follow these steps

  1. Depends as follows:

When

Action

Test is performed regularly (as part of the maintenance plan)

Run the script: D02 - Test System Tightness (What Should Be Tested = System).

Test is performed because

  • A leak sensor reports leakage.

  • Chromatography problems are observed.

1. Run the script: D02 - Test System Tightness (What Should Be Tested = System).

2. Run the script: E04 - Detailed Leak test (Pump)

  1. Check the test result. If the script reports a leakage, resolve the leakage following the instructions on the screen.

  2. To verify that the leakage has been fully resolved, run the script again and check the result.