Product component

What you should do...

System/all modules

  • Replace the solvent reservoirs every 1 or 2 weeks. To replace the solvent reservoirs, run the script: B01 - Change Liquids / Solvents. Before filling reservoirs, rinse them thoroughly.

  • Inspect the system for leakage: D02 - Test System Tightness (What Should Be Tested = System).

  • Replace the solvent line filter frits at regular intervals. This is especially important when using aqueous solvents. Aqueous solvents may contaminate the filters with algae and other microorganisms that deposit on the filter frits.

  • Inspect the flow connections for damage, such as cracks, nicks, cuts, or blockage.

  • Check the drain system for blockage. See Testing the Drain System.

  • Empty the waste containers.

  • Clean the system. See Cleaning or Decontaminating a System Module or the System.

  • Inspect the warning labels on the system and its modules. If a warning label is missing or illegible, contact Thermo Fisher Scientific for replacement.

Wash systems

  • Needle wash systems:

    Replace the needle wash reservoirs regularly, approximately every 1 or 2 weeks. To replace the needle wash reservoirs, run the script: B01 - Change Liquids / Solvents.

  • Seal wash system:

    • Replace the seal wash reservoir. Rinse the reservoir thoroughly before filling it. Use a high-purity solvent for rinsing.

    • Inspect the seal wash lines. If a line is blocked (squeezed or bent), replace the line.

    • Inspect the peristaltic tubing in the seal wash pump. If it is dislocated or hardened, reposition or replace the tubing. See Replacing the Peristaltic Tubing in the Seal Wash Pump. Replace the tubing every 6 months as preventive maintenance.

    • Test the seal wash system for leakage. See Testing the Seal Wash System for Leakage.

Pump

Autosampler

  • Replace the drain pump tubing every 6 months. See Replacing the Drain Pump Tubing.

  • (Heated) Trap-and-elute workflow only: Determine the backpressure of the trap column flow path. Run the script: D01 - Test System Back Pressure with the parameter: Test only trap column resistance. Write down that value and compare with subsequent backpressure tests to evaluate the trap column aging.

Display

Retighten the screws fixing the display to the system.