To optimize the column compartment performance, consider the following general guidelines:
Use short connection capillaries.
Monitor the usage of specific column compartment components, for example, column switching valves that are subject to wear and stress and schedule appropriate maintenance intervals (see Predictive Performance).
Always close the column chamber cover and the column compartment door during operation.
Observe the general guidelines and recommendations on the use of solvents and additives in the chromatography system. Refer to Use of Solvents and Additives in the Vanquish System Operating Manual.