To protect optimal functionality of the Vanquish system, observe these recommendations on the use of solvents and additives:
By default, the system must be used with reversed-phase (RP) compatible solvents and additives only.
TIP
The charged aerosol detector can also be used in a Vanquish system with normal-phase (NP) compatible solvents and additives if the system modules have been modified for NP applications. Refer to the Vanquish System Operating Manual.
Use only solvents and additives that are compatible with all parts in the flow path.
Piston Seal Compatibility
In rare cases, a shortened lifetime of reversed-phase (UHMW-PE) piston seals has been observed with high pH, ammonium hydroxide containing mobile phases and prolonged exposure.