To protect optimal functionality of the Vanquish system, observe these recommendations on the use of solvents and additives:

  • By default, the system must be used with reversed-phase (RP) compatible solvents and additives only.

TIP

The charged aerosol detector can also be used in a Vanquish system with normal-phase (NP) compatible solvents and additives if the system modules have been modified for NP applications. Refer to the Vanquish System Operating Manual.

  • Use only solvents and additives that are compatible with all parts in the flow path.

Piston Seal Compatibility

  • In rare cases, a shortened lifetime of reversed-phase (UHMW-PE) piston seals has been observed with high pH, ammonium hydroxide containing mobile phases and prolonged exposure.