To interrupt operation for a longer period, follow the instructions below.
NOTICE
Observe the following to avoid damage to the charged aerosol detector:
TIP
Shutting down the device affects the operation of the system. When shutting down the device, also observe the shutting down instructions for the other Vanquish system modules and take appropriate action (refer to the Operating Manuals for the modules).
Remove the column.
Flush the system with an appropriate solvent (minimum HPLC-grade). Observe the following:
Situation after Shutdown | If no additive is used | If an additive is used |
---|---|---|
Device remains in the laboratory after shutdown | Flush the system, for example with methanol. 100% acetonitrile should not be used. | Flush the system with several volumes of methanol and water (50:50) (for example, 1.0 mL/min for 10 minutes with the standard system) to prevent salt buildup in the fluidics. If the solvents in the device are not miscible with water, use an appropriate intermediate solvent. |
Device shall be transported or shipped after shutdown | Flush the system with isopropanol. | Flush the system first with several volumes of methanol and water (50:50) (for example, 1.0 mL/min for 10 minutes with the standard system) to prevent salt buildup in the fluidics. If the solvents in the device are not miscible with water, use an appropriate intermediate solvent. Afterward, flush the system with isopropanol. |
Make sure that residual sample components, impurities from the column or buffers are completely removed from the detector.
TIP
As an intermediate solvent, you can use 100% methanol to flush the charged aerosol detector.
Turn off the pump flow and then the gas flow:
- Turn off the pump flow to the detector.
- Wait at least 30 minutes. During the waiting period, the detector drains any remaining mobile phase to waste.
NOTICE
Damage to the detector
Turning off the gas glow too early may result in condensation and, thus, to deterioration of detector parts and/or flooding.
- Turn off the gas flow on the detector.
- Wait until the system pressure is down to zero before you continue.
- Turn off the gas supply to the detector.
The step depends as follows:
Situation | Steps |
---|---|
Device and all other system modules remain in the system stack and are to be turned off | Turn off the system with the system power button on the system base. |
Device shall be transported or shipped after shutdown | If one of the modules shall be removed from the system stack, turn off all system modules with their main power switch. Pressing the system power button will not be sufficient to turn off the power to the devices completely. Follow the instructions in Transporting or Shipping the Device. |