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Top Down Analysis User Guide

Product Tree
Ardia Platform > Software > BioPharma Finder Software
Desktop Software > BioPharma Finder Software
Document Type
User Guide
Software version
5.4
  • BioPharma Finder
  • Getting started
  • About BioPharma Finder
  • New in this version
  • Special notices
  • Contact us
  • Data acquisition and component identification
  • Supported fragmentation methods
  • Start the application
  • Connect to the Ardia Platform
  • Register with the Ardia Platform
  • Sign in to your Ardia Platform account
  • Ardia Platform management
  • Results from earlier BioPharma Finder software versions
  • View, revert, and compare experiment versions
  • Exit the application
  • Data backup and recovery
  • Create or restore a database Snapshot
  • Manual database backup
  • Data space optimization
  • Create a new experiment
  • Start and name an experiment
  • Select raw data files
  • Add raw data files
  • Delete raw data files
  • Specify conditions
  • Result formats: Batch Processing and Multiconsensus
  • Select sequences
  • Select a processing method
  • Specify a processing method
  • Import a processing method
  • Export a processing method
  • Delete a processing method
  • Automatic parameter values
  • Use the run queue
  • Queue manipulation
  • Run queue table information
  • Open results
  • Organize experiment results on the Load Results page
  • Manage experiments in the Master List
  • Organize folders and experiments in the Working List
  • Introduction to BioPharma Finder workbooks
  • Manage workbooks
  • Workbook Manager commands
  • Workbook Manager table information
  • Create a target peptide workbook
  • Save experiment results to a target peptide workbook
  • Add theoretical components to a target peptide workbook
  • Specify target peptide workbook parameters
  • Peptide Workbook Editor Results table information
  • Peptide Workbook Editor commands
  • Create an oligo workbook
  • Save experiment results to an oligo workbook
  • Add theoretical sequences to an oligo workbook
  • Manually add sequences
  • Use a CSV file to add sequences
  • Specify oligo workbook parameters
  • Oligonucleotide Calculator and Workbook Editor Results table information
  • Oligonucleotide Calculator and Workbook Editor commands
  • Create an intact workbook
  • Save experiment results to an intact workbook
  • Intact Workbook Editor Results table information
  • Intact Workbook Editor commands
  • Use the Sequence Manager
  • Sequence Manager tasks
  • Sequence Manager table information
  • Using the Host Cell Protein Database Manager
  • Using the Theoretical Protein/Peptide Manager
  • Create or import a protein sequence
  • Specify digestion parameters
  • Add/edit target m/z parameters
  • Add/edit modifications
  • Generate and save theoretical components
  • Theoretical Protein/Peptide Manager Results table information
  • Theoretical Protein/Peptide Manager commands
  • Create protein sequences
  • Manually create a new protein sequence
  • Import a FASTA file containing a protein sequence
  • Assign modifications to a protein sequence
  • Manage disulfide links
  • Disulfide Link Definitions table information
  • Manage static modifications
  • Residue Properties and Modifications dialog box parameters and commands
  • Manage glycosylations
  • Manage variable modifications
  • Variable Modifications for Intact and Peptide Analysis pane parameters and commands
  • Define default modifications for protein sequences
  • Define Modification List table information
  • Default sublist of modifications for quick-loading
  • Create custom variable modifications
  • Modification Editor pane parameters and commands
  • Manage proteoforms
  • All Possible Proteoforms table information
  • Save a protein sequence
  • Protein Sequence Editor parameters and commands
  • Amino acid letter codes
  • About Top Down Analysis
  • Run a Top Down Analysis experiment
  • Work with a Top Down Analysis processing method
  • Component Detection parameters
  • Peak Selection parameters
  • ReSpect deconvolution parameters
  • Xtract deconvolution parameters
  • Plots on the Component Detection page
  • Identification parameters
  • Sequences for Top Down Analysis experiments
  • Save Experiment page
  • View Top Down Analysis results
  • Use real-time optimization (RTO) to reprocess results
  • Process and Review page
  • View the Results tables
  • Change the reference mass
  • Intact Fragmentation Results table parameters
  • Intact Deconvolution Results table parameters
  • Export the Results tables
  • Results tables commands
  • View the chromatograms
  • Chromatogram plot types
  • Chromatogram pane commands
  • View the deconvoluted spectra
  • Deconvoluted Spectrum panes commands
  • View the source spectra
  • Source Spectrum panes commands
  • View the ProSightBP Fragment Map
  • Matching Fragment Detail table parameters
  • ProSightBP Fragment Map pane commands
  • View the ProSightBP Output Results table
  • Export the ProSightBP Output Results table
  • ProSightBP Output Results table parameters
  • ProSightBP Output pane commands
  • View the matched sequence information
  • Change the matched sequence identification for a component
  • Component Information table parameters
  • Target Match Sequence table parameters
  • Process and Review page parameters
  • Process and Review page commands
  • Reference information
  • Data conversion from legacy applications
  • Converted sequences
  • Converted processing methods
  • Appendix: Handling errors
  • Database service errors
  • Other errors
  • Appendix: Interactive functions
  • Copy and paste functions
  • Copy all contents in a pane
  • Copy a portion of contents in a pane
  • Organize panes
  • Basic chromatogram functions
  • Basic spectrum functions
  • Basic table functions
  • Sort rows
  • Show or hide columns
  • Filter data in a table
  • Filter data rows
  • Table filter operators
  • Table filter operands
  • Create, save, and apply custom filters
  • Remove filters
  • Save filters to a file
  • Apply saved filters to data
  • Appendix: Glycans
  • N-linked glycans in the Define Modification List window
  • N-linked glycans with a CHO host cell-line type
  • N-linked glycans with a human host cell-line type
  • O-linked glycans
  • References
  • Copyright Information

You can find information on all of the different support services of Thermo Fisher Scientific by navigating the following website:
https://www.thermofisher.com/us/en/home/technical-resources/contact-us.html

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