For the APCI ion source, the recommended setting for the Corona Discharge Voltage depends on the polarity:

  • Positive ion discharge current: 4 μA
  • Negative ion discharge current: 10 μA
Recommended LC/APCI/MS parameters

LC Flow Rates (μL/min)

<=14.99

15–99.99

100–199.99

200–499.99

500–999.99

1000–3000

Sheath gas (arb)

10

15

25

45

45

45

Aux gas (arb)

2

5

5

5

10

10

Sweep gas (arb)

0

0

0

1

2

2

Vaporizer temp (°C)

0

275

325

350

400

400

Nitrogen consumption (L/min)

4

7

8

12

16

16

Ion transfer tube temp (°C)

TSQ Altis Plus,
TSQ Altis,
and TSQ Quantiva

300

300

300

325

375

375

TSQ Quantis Plus,
TSQ Quantis,
and TSQ Endura

275

275

275

300

325

350

Fortis Plus and Fortis

250

250

250

275

300

325