The API source forms gas phase sample ions from sample molecules that are contained in solution. The API source also serves as the interface between the LC and the MS. You can use the ion source that comes with your TSQ Series II mass spectrometer to use the heated electrospray ionization technique (H-ESI).
NOTE
For information about all the compatible ion sources for your instrument, see Compatible ion sources.
To run the mass spectrometer in the APCI mode or the APPI mode with the OptaMax NG ion source, you must order additional kits. Refer to the OptaMax NG Ion Source User Guide for ordering information.
The optional Thermo Scientific VeriSpray PaperSpray ion source that is compatible with the TSQ Series II mass spectrometers does not use an external LC system and autosampler to introduce sample into the ion source.
The MS has a built-in drain at the front of the system that routes the solvent waste from the API source to the solvent waste container connected to the left-side drain/waste port. For information about the solvent waste connection, refer to the Getting Connected Guide for your mass spectrometer.
The TSQ Endura MS shipped with the EASY-Max NG™ ion source, and the TSQ Quantiva MS shipped with the Ion Max NG™ ion source. The Ion Max NG ion source has an additional feature for adjusting the depth of the spray insert that the EASY-Max NG ion source lacks.
| No. | Description | No. | Description |
|---|---|---|---|
1 | API spray insert depth adjustment lever | 5 | Left-to-right adjustment knob (located on the left and right side) |
2 | Grounding union holder | 6 | Window |
3 | Retainer knob for the API spray (located on the left and right side) | 7 | Drain insert |
4 | Locking lever (the left and right side are shown in the locked position) |
The following figure shows the position markers on the Ion Max NG ion source.
| No. | Description | No. | Description |
|---|---|---|---|
1 | Left-to-right position markers | 2 | Front-to-back position markers |
With the exception of the TSQ Endura MS (which only ships to selected countries), all the models in the TSQ Series II product line that are currently shipping come with the OptaMax NG ion source.
The OptaMax NG ion source is APCI ready; that is, it has a built-in corona discharge needle mount inside the housing and an APCI On/Off control knob on the exterior right side of the housing.
| No. | Description | No. | Description |
|---|---|---|---|
1 | Grounding union holder | 6 | APCI On/Off switch |
2 | API spray insert depth adjustment lever | 7 | APCI needle mount |
3 | Retainer knob for the API spray insert and heater assembly (located on the left and right side) | 8 | Window |
4 | Locking lever (the left and right side are shown in the locked position) | 9 | Drain insert |
5 | Left-to-right adjustment knob (located on the left and right side) |
The OptaMax Duet ion source is a separate option that you can purchase from Thermo Fisher Scientific. The OptaMax Duet ion source includes depth and side-to-side adjustment for the API spray insert. It also includes a built-in corona discharge needle that you can turn on or off from the software controls.
| No. | Description | No. | Description |
|---|---|---|---|
1 | Grounding union holder | 5 | Left-to-right adjustment knob (located on the left and right side) |
2 | API spray insert depth adjustment lever | 6 | Corona discharge needle for the APCI |
3 | Retainer knob for the API spray (located on the left and right side) | 7 | Drain insert |
4 | Locking lever (the left and right side are shown in the locked position) |