LC Additive Guidelines - Stellar MS - Stellar Mass Spectrometer Operating Manual - LC Additive Guidelines - Operation - Stellar MS

If your workflow requires the use of the following reagents, contact Thermo Fisher Scientific Technical Support for advice.

Limit the type of reagents you use, if possible:

• Because it reacts with the PEEK material, do not use tetrahydrofuran (THF).
• Because these might cause corrosion of the API source, do not use the following:
• Alkali-metal bases, such as sodium hydroxide (NaOH)
• Inorganic acids, such as hydrogen chloride (HCl), phosphoric acid (H₃PO₄), or sulfuric acid (H₂SO₄)

• Because these reagents can suppress ionization, do not use the following:
• Detergent solutions
• Nonvolatile buffer solutions, such as borate, citrate, or phosphate
• Surfactants or other surface-active agents, such as polyethylene glycol (PEG), sodium dodecyl sulfate (SDS), or Triton™ X-100
• Trifluoroacetic acid (TFA) at concentrations (volume/volume %) greater than 0.1