Full Scan - Stellar MS - Stellar Mass Spectrometer Operating Manual - Full Scan - Software - Scan Parameters - Scan Types - Stellar MS

The full scan (MS¹) experiment performs a single stage of mass analysis; that is, a scan power of n = 1.

As with all scan types, the ion source forms ions that enter the analyzer assembly. The quadrupole mass analyzer isolates a wide user defined m/z range. The ions pass from the quadrupole mass analyzer and move to the ICRM quadrupole assembly where they are stored, then transmitted to the dual-pressure linear ion trap where they enter and are trapped in the high-pressure cell, pass to the low-pressure cell, and are mass analyzed. The resulting mass-selected ions are finally detected by the ion detection system.

MS¹ experiments can be useful to determine the precursors that are present in a sample, and to perform experiments like data-dependent analysis (DDA). Even for data-independent analysis (DIA), some processing algorithms make use of MS¹ scan information. With the Stellar MS, MS¹ scans are usually not as useful as MS¹ scans on high resolution instruments, and interference from other compounds of similar m/z can be an issue. Nevertheless, some experimenters include MS¹ scans in their methods to serve as a diagnostic, and also because TIC normalization in targeted analysis programs, such as Skyline, is enabled by including MS¹ scans, even if those scans are not utilized for quantification.