The CHIMERYS Inclusion File performs Match Between Runs (MBR) one file at a time using the PSMs in the inclusion file as the targets to try to quantify. Thermo Fisher Scientific recommends using this parameter for very large datasets where the One Job Per File parameter is not a possible option.

The CHIMERYS inclusion file must only include PSMs from the peptides you would like to quantify across all runs. Adding too many PSMs to the inclusion file might negatively affect the number of identified and quantified peptides.

NOTE

The CHIMERYS Inclusion Files page is only available if you have a CHIMERYS license.