The searches started by the Proteome Discoverer application consume memory and can potentially cause the data-acquiring computer to crash and lose the sample in the mass spectrometer. To avoid this outcome, Thermo Fisher Scientific recommends that you connect the Proteome Discoverer Daemon utility to a remote computer running the Magellan server before data acquisition.
Procedure
- Start the Proteome Discoverer application on the remote server.
- To store the output files in a location other than the default folder, do the following:
- Select Administration > Configuration > Server Settings > Discoverer Daemon.
- The PublicFiles folder is the default folder displayed in the Current File Directory box.
- In the New Directory box, locate the storage location for the output files.
- Select Apply.
- The Daemon utility issues a message informing you that the Proteome Discoverer application will apply the change the next time that you start it.
- To return to the default directory, select Reset.
- Start the Daemon utility on the local machine.
- A message box informs you that the utility cannot connect to the server.
- Select OK in the message box.
- The utility opens with the Configuration page selected.
- In the Host box, enter the name of the remote computer.
- In the User box, enter the login name of the remote server.
- In the Access Token box, paste in the remote server Daemon Access Token.
- Select Apply.