The searches started by the Proteome Discoverer application consume memory and can potentially cause the data-acquiring computer to crash and lose the sample in the mass spectrometer. To avoid this outcome, Thermo Fisher Scientific recommends that you connect the Proteome Discoverer Daemon utility to a remote computer running the Magellan server before data acquisition.

Procedure

  1. Start the Proteome Discoverer application on the remote server.
  2. To store the output files in a location other than the default folder, do the following:
  3. Select Administration > Configuration > Server Settings > Discoverer Daemon.
  4. The PublicFiles folder is the default folder displayed in the Current File Directory box.
  5. In the New Directory box, locate the storage location for the output files.
  6. Select Apply.
  7. The Daemon utility issues a message informing you that the Proteome Discoverer application will apply the change the next time that you start it.
  8. To return to the default directory, select Reset.
  9. Proteome Discoverer Daemon area of the Configuration view
  10. Start the Daemon utility on the local machine.
  11. A message box informs you that the utility cannot connect to the server.
  12. Select OK in the message box.
  13. The utility opens with the Configuration page selected.
  14. In the Host box, enter the name of the remote computer.
  15. In the User box, enter the login name of the remote server.
  16. In the Access Token box, paste in the remote server Daemon Access Token.
  17. Select Apply.