The Proteome Discoverer application gives you access to protein annotation information from a web service that provides the following from the UniProt database:
- Gene ontology (GO) molecular function, cellular component, and biological process terms
- Reactome and WikiPathways pathway annotations
- Protein Family (Pfam) classification information
- HGNC gene symbols and Entrez gene identifications
- Genomic annotations of genetically sequenced organisms from the Ensembl genome database
- Post-translational modification information
The protein annotations web service is updated on a regular basis. The protein annotation service also lets you download full proteome databases by taxonomy number. For more information about downloading FASTA files, see Download FASTA files to Proteome Discoverer.