These are the minimum hardware and software configurations required for Proteome Discoverer 3.1 operation.

System

Requirements

PC

  • 2 GHz processor (2.5 GHz or higher with multiple cores recommended)
  • 16 GB RAM (64 GB RAM recommended)
  • 75 GB available on C drive (1 TB Boot and data SSD drives recommended)
  • NTFS format
  • Microsoft .NET Framework 4.8
  • Microsoft .NET Runtime 7.0.10
  • ASP .NET Core Runtime 7.0.10
  • Discoverer Daemon can only be directly called by Xcalibur 4.3 or later
  • Windows 10 Professional or Windows 11 Professional
  • Network connection required for CHIMERYS search and Protein Annotation node. Other Proteome Discoverer features available without a network connection.