The table below lists all known issues that exist in the Orbitrap Hybrid Series 5.1 Instrument Control Software release.

Table Known Issues

ID

Severity

Title

153093

3 - Medium

Divert Valves need to be Configured for USB Control.
Remedy: The divert valves can be controlled through interfacing with a computer. Download the MX Series II™ Control Software Program to configure the divert valves for Orbitrap Exploris: www.idex-hs.com/literature-tools/software-drivers/

153505

3 - Medium

Installer blocks workstation installation (Method Editor standalone) if there is already a Full Installation on the data system PC.
Remedy: Run Workstation installation on a different computer. Installer supports simultaneous Workstation installation of all Orbitrap Exploris instrument models.

153665

3 - Medium

Orbitrap Exploris 480 DVD ISO image: Software Uninstallation Error.

154441

3 - Medium

Tune: Display imperfect on 4 k monitor.

153627

3 - Medium

Tune: Under certain conditions, wrong number of errors and warnings is shown.

828949

3 - Medium

Tune: Graph for Mass Calibration in Tune gets replaced by "Adjust HCD cell pressure to standard pressure" when running from Intact Protein Mode with Standard pressure setting

153432

2 - High

UI: Method Editor: MIPS filter incompatible with Targeted Mass filter.
Remedy: Do not use MIPS Filter with Targeted Mass Filter.

214267

3 - Medium

Chromeleon: sporadic communication loss to Thermo Exploris Series ePanels.
Remedy: This may happen sporadically during standby or after a sequence has finished. Restarting Chromeleon allows regain control of Thermo Exploris Series ePanel.

233537

3 - Medium

Chromeleon periodically shuts down with a message “The target application domain has been unloaded.”
Remedy: Launch Chromeleon after shutdown. The sequence keeps on running without data loss.

357682

2 - High

Instrument Configuration: the “Wait for Temperatures to Stabilize checkbox” is not functional after an Instrument PC restart.
Remedy: Restart Instrument PC two times after enabling or disabling the configuration setting.

683124

3 - Medium

Customer/Tune: Favorites are not saved in the correct folder when upgrading from Exploris 4.2 SP4 to Exploris 4.3
Remedy: Copy the files from the Program Files location into the Program Data location.

758688

3 - Medium

Status Indicator doesn't turn red after Venting & Bakeout as supposed according fo Acceptance Criteria

828210

3 - Medium

System Calibration - IC Source calibration: Instructions panel (white box) shows incomplete feedback when procedure fails

843001

2- High

Max Injection Time: "Auto" does not take ETD overheads into account

844390

3 - Medium

Sequence stopped due to a commuincation issue between SII and Vanquish Neo

777178

2 - High

Sporadic DAQ USB misalignment errors during LC/MS sequence acquisition (Babble Error)