The BioPharma Finder application provides several default processing methods for Intact Mass Analysis experiments.

For more information on the two deconvolution algorithms used by the application, see Deconvolution algorithms.

Default Intact Mass Analysis processing methods

ReSpect

Xtract

  • Default ReSpect: Default processing method for low-resolution, isotopically unresolved protein MS data using the Average Over Selected Retention Time method.
  • Default Oligo ReSpect: Default processing method for low-resolution, isotopically unresolved oligonucleotide MS data using the Average Over Selected Retention Time method.
  • Default SW ReSpect: Default processing method for low-resolution, isotopically unresolved MS data using the Sliding Windows method.
  • Default Auto ReSpect: Default processing method for low-resolution, isotopically unresolved MS data using the Auto Peak Detection method.
  • Default Xtract: Default processing method for high-resolution, isotopically resolved protein MS data using the Average Over Selected Retention Time method.
  • Default Oligo Xtract: Default processing method for high-resolution, isotopically resolved oligonucleotide MS data using the Average Over Selected Retention Time method.
  • Default SW Xtract: Default processing method for high-resolution, isotopically resolved MS data using the Sliding Windows method.
  • Default Auto Xtract: Default processing method for low-resolution, isotopically unresolved MS data using the Auto Peak Detection method.
  • Pierce Intact Protein Standard Low Res LC Method: Default processing method for low-resolution LC/MS calibration experiments using Pierce intact protein standard.
  • Pierce Intact Protein Standard Low Res Infusion Method: Default processing method for low-resolution direct infusion MS calibration experiments using Pierce intact protein standard.
  • Pierce Intact Protein Standard Mix High Res LC Method: Default processing method for high-resolution LC/MS calibration experiments using Pierce intact protein standard.
  • Pierce Intact Protein Standard Mix High Res Infusion Method: Default processing method for high-resolution direct infusion MS calibration experiments using Pierce intact protein standard.
  • Default IonTrap, ISQ, and TSQ: Default processing method for IonTrap, ISQ, and TSQ MS data.
  • Default ADC: Default processing method for antibody-drug conjugate (ADC) MS data.
  • Default Native: Default processing method for structural analysis of large intact proteins.
  • Default Native Above 1 Million: Default processing method for structural analysis of large intact proteins with a molecule weight over 106 Da.