In the Protein Sequence Editor, you can prompt the application to search for over 200 potential N- and O-linked glycans.
NOTE
The application supports N-linked glycans for both Peptide Mapping Analysis and Intact Mass Analysis experiments, but O-linked glycans are supported for Peptide Mapping Analysis experiments only.
Prerequisites
- You are editing a protein sequence in the Protein Sequence Editor.
- The sequence has the "Peptide Mapping" category for Peptide Mapping Analysis or the "Intact Protein" category for Intact Mass Analysis.
Procedure
- In the Protein Sequence Editor, expand the Variable Modifications for Intact and Peptide Analysis pane on the right side of the page.
- At the top of the pane, in the Glycosylation area, select the glycan database (or None) to use in the glycosylation search from the N, O Glycan dropdown list:
- None: Does not add a search for glycans.
- CHO: Adds a search for glycans from the Chinese hamster ovary (CHO) database.
- Human: Adds a search for glycans from the human glycan database.
- Save the protein sequence.