The following table lists the default modifications included in the sublist for quick-loading.

Default sublist of modifications for quick-loading

Category

Default modifications

5'-Terminal

  • Dephosphorylation

3'-Terminal

  • Dephosphorylation

Base

  • Adenine loss (A)
  • Uracil loss (U)
  • Cytosine loss (C)
  • Guanine loss (G)
  • Thymine loss (T)
  • Deamination (AC)
  • Oxidation (ACGU)
  • G Depurination (G)
  • U Depyrimidination (U)
  • C Depyrimidination (C)
  • T Depyrimidination (T)
  • I Depurination (I)
  • Acetyl group (AGC)
  • Benzoyl group (AC)
  • Isobutyl group (G)

Backbone linker

  • Cnet (ps)
  • Sulfur loss (s)
  • Phosphorothioate conversion (s)

2'-ribose

  • HF loss (f)