The Dionex EGC requires at least 14 MPa (2000 psi) of system backpressure for removal of electrolysis gas from the eluent produced by the cartridge. A system backpressure of 16 MPa (2300 psi) is ideal.
If the system backpressure is too low, Thermo Fisher Scientific recommends connecting a backpressure coil (P/N 053765) between the injection valve and the Dionex EG DEGAS OUT port. For more information, see Install an eluent generator cartridge (Dionex EGC).