For the Dionex ADRS 600, this problem is caused when the ion exchange sites in the suppressor are converted from the hydronium form to the salt form. They must be converted back to the hydronium form for efficient operation.
For the Dionex CDRS 600, this problem is caused when the ion exchange sites in the suppressor are converted from the hydroxide form to a salt form. They must be converted back to the hydroxide form for efficient operation.
Procedure
- Regenerate the suppressor as outlined in Small or increasing analyte peak areas. If capacity remains low, clean the suppressor membrane (see Cleaning the suppressors).