If the increased back pressure does not affect system performance, no maintenance is necessary.

Procedure

  1. Check the inlet frits on the guard and analytical column and replace them if necessary. The most common cause of increasing system back pressure is a contaminated frit in the analytical or guard column inlet end fitting.
  2. The complete instructions for replacing column bed support assemblies are in Document No. 032285. Recheck the system back pressure. If it remains high, go on to the next step.
  3. Check the backpressure coils. If removing the backpressure coils lowers the pressure by more than 40 psi, replace the coils or remove the blockage causing the increased pressure. Backpressure over 450 psi after the suppressor can cause irreversible damage.
  4. Find and eliminate any system blockage. Bypass the Dionex DRS 600, Dionex ERS 500e or Dionex AERS 500 Carbonate by coupling the lines attached to the ELUENT IN and ELUENT OUT ports. If the back pressure decreases by less than 150 psi with the suppressor out of line, a blockage in the system rather than in the suppressor is causing the high pressure.
  5. Remove a blockage from the suppressor by reversing the eluent flow. If the back pressure decreases by more than 150 psi with the suppressor out of line, the high pressure may be caused by a blockage in the suppressor. Reverse the direction of flow of both the eluent and the external water through the suppressor. After the pressure drops, allow eluent, or eluent and regenerant, to flow to waste for several minutes after the pressure drops. Perform Step 1 of Start-up and reinstall the suppressor in the appropriate configuration.
  6. Clean the suppressor membranes if reversing the flow through the suppressor does not decrease the pressure (see Cleaning the suppressors).
  7. Replace the suppressor if cleaning the suppressor membrane does not reduce the pressure.

Contact the nearest Thermo Fisher Scientific Regional Office if you cannot solve the problem on your own.