Decreased sensitivity for magnesium and calcium only (CDRS 600 and CERS 500e suppressors) - ERD 500 - ERS 500e - ERS 500 Carbonate - DRS 600 - Decreased sensitivity for magnesium and calcium only (CDRS 600 and CERS 500e suppressors) - ERD 500 - ERS 500e - ERS 500 Carbonate - DRS 600

Procedure

1. Check for leaks throughout the system. If a fitting is leaking, tighten it carefully until the leak stops. Do not over tighten.
2. If the suppressor is leaking from the center or bottom seam, see Liquid leaks.
2. Ensure that the injection valve is operating correctly. Refer to the valve manuals that accompany the chromatography module for troubleshooting assistance. For slider valves, be sure to check the slider port faces for damage.
3. Regenerate the suppressor:
1. Pump approximately 15ml of 500mM MSA through the suppressor to re-dissolve any calcium or magnesium hydroxide precipitates that may be present. Flush with 10 mL degassed, deionized water through the ELUENT OUT port and REGEN IN port.
2. Pump 15 mL of freshly prepared 200 mN NaOH (made up using degassed, deionized water) through the ELUENT OUT port and REGEN IN port. Flush with 10 mL degassed, deionized water through the ELUENT OUT port and REGEN IN port.
4. Replace the suppressor if cleaning the suppressor membrane does not restore sensitivity.