Procedure
- Check for leaks throughout the system. If a fitting is leaking, tighten it carefully until the leak stops. Do not over tighten.
- If the suppressor is leaking from the center or bottom seam, see Liquid leaks.
- Ensure that the injection valve is operating correctly. Refer to the valve manuals that accompany the chromatography module for troubleshooting assistance. For slider valves, be sure to check the slider port faces for damage.
- Regenerate the suppressor as outlined in Small or increasing analyte peak areas.
- If sensitivity remains low, clean the suppressor membrane as outlined in Cleaning the suppressors.
- Check the backpressure coils. Verify that they are not exceeding 40 psi in the current plumbing configuration and flow rate.
- Replace the suppressor if cleaning the suppressor membrane does not restore sensitivity.
Contact the nearest Thermo Fisher Scientific Regional Office if you cannot solve the problem on your own.