The Dionex ADRS 600 or Dionex AERS 500e can be used for suppression of MPIC (ion-pairing) eluents by using the MPIC Suppression Mode. The MPIC Suppression Mode is a combination of the Auto Suppression External Water Mode augmented with a chemical regenerant such as sulfuric acid (H2SO4). When a Dionex ADRS 600 or Dionex AERS 500e is operating in this mode, it uses an applied current and a constant source of dilute sulfuric acid solution from a pressurized bottle delivery system or additional pump.

The following table lists the eluent concentrations and flow rates of standard eluents used in Anion MPIC separations and the current level and regenerant flow rate required to suppress them.

NOTE

The Dionex AERS 500 Carbonate suppressor is not recommended for use with the MPIC Suppression Mode of Operation. The Dionex ADRS 600 or Dionex AERS 500e should be used.

Matching the Current Setting and Regenerant Flow Rate to the Eluent Concentration and Flow Rate for the Dionex ADRS 600 (4 mm) or Dionex AERS 500e (4 mm) in the MPIC Suppression Mode

Eluent

Eluent Flow Rate
(mL/min)

Current
(mA)

Regenerant Flow
Rate (mL/min)1)

Regenerant
Concentration (mN)

0.1–2.0 mM TBAOH

0.5–2.0

50/100

3–5

5–10

2.0–5.0 mM TBAOH

0.5–1.0

100/300

3–5

10

 

1.1–1.5

300/500

3–5

10

NOTE

For lower eluent concentration in a given range, choose lower corresponding current; for higher eluent concentration, choose a higher current setting. Higher current settings require higher pressures applied to the pressurized regenerant delivery bottle to maintain adequate regenerant flow.