NOTE

You can edit a custom modification or building block only if the subunit is not currently used in any sequences loaded to the Sequence Manager.

Otherwise, you must first modify the affected sequences to remove the subunit. After you edit the subunit, you can modify the affected sequences again to re-add the edited custom modification or building block.

Procedure

  1. In the Oligonucleotide Sequence Editor, select the title bar for the Building Block and Variable Modification Editor.
  2. The Building Block and Variable Modification Editor pane opens, displaying the Oligo Building Block and Oligo Variable Modification areas.
  3. At the bottom of the pane, a table lists all of the custom building blocks and variable modifications.
  4. Existing custom modifications appear in purple in the table.
  5. In the table, select the subunit you want to modify and select Edit.
  6. The building block or modification information appears in the appropriate editor above the table.
  7. Change the subunit, name, symbol or site, mass, and formula information in the editor as needed.
  8. Select Apply.
  9. The application overwrites the existing building block or variable modification with the new information.