Advanced settings for the Genesis algorithm - Ardia Data Viewer - Ardia Data Viewer Application 1.1 Functional Specifications - Advanced settings for the Genesis algorithm - Peak Detection page - Peak detection algorithm - Info Bar - Ardia Data Viewer

Report Noise As

N/A

Specifies the parameters used to calculate the  S/N values.

RMS

Radio button

Calculates noise as an RMS. The algorithm uses the peak-to-peak method for the noise calculation. When the user determines the noise region manually, the algorithm automatically selects the RMS option.

Peak to Peak

Radio button

Calculates noise as a peak-to-peak value.

Manual Noise Region

Checkbox

Specifies a region of the chromatogram that the peak detection algorithm uses to determine noise.

RT Range

N/A

Specifies the RT range that the algorithm uses to determine noise. The RT range must be within the chromatogram range.

Baseline Noise Tolerance (%)

N/A

Specifies a percentage value that controls how the algorithm draws the baseline in the noise data. The higher the baseline noise tolerance value, the higher it draws the baseline through the noise data.

Range: 0.0–100.0; default: 10.0.

Min Number of Scans in Baseline

N/A

Specifies the minimum number of scans that the algorithm uses to calculate a baseline. A larger number includes more data in determining an averaged baseline.

Range: 2–100; default: 16.

Baseline Noise Rejection Factor

N/A

Specifies the baseline noise rejection factor. This factor controls the width of the RMS noise band above and below the peak detection baseline.

Range: 0.1–10.0; default: 2.0.

Peak S/N Cutoff

N/A

Specifies the S/N level that the algorithm defines as the top of the peak edge. For example, if the S/N level at the apex is 500 and the Peak S/N Cutoff value is 200, the algorithm defines the right and left edges of the peak as the points when the S/N reaches a value less than 200.

Range: 50.0–10,000.0; default: 200.0.

Rise Percentage

N/A

Specifies how much above the baseline the trace can rise (as a percentage) after passing through a minimum inflection point in the trace (before or after the peak). If the trace exceeds this value, the algorithm applies valley detection peak integration criteria. The rise percentage criterion is useful for integrating peaks with long tails.

Range: 0.1–500.0; default: 10.0.

Valley S/N

N/A

Specifies the S/N criterion that the algorithm uses for valley detection.

Range: 1.0–100.0; default: 1.0.

Background Recomputation (min)

N/A

Specifies the background recomputation interval (in minutes). The algorithm periodically recalculates the representative background scan it uses for background subtraction to compensate for the possibility that the composition of the background might change over the course of a run. The background recomputation interval is the time interval between these recalculations.

Range: 0.5–10.0; default: 5.0.

Number of Scans in Background

N/A

Specifies the number of background scans the algorithm uses to determine the background.

Range: 2–100; default: 5.